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Comparison of clinical presentations and outcomes between adult and elderly acute myocardial infarction patients in emergency department

  
@article{HT5325,
	author = {Po-Hua Su and Pang-Yen Chen and Shih-Yi Lee and Chorng-Kuang How and Ding-Kuo Chien and Wen-Han Chang},
	title = {Comparison of clinical presentations and outcomes between adult and elderly acute myocardial infarction patients in emergency department},
	journal = {Health Technology},
	volume = {3},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Background: Acute myocardial infarction (AMI) is one of a leading cause of death. The clinical presentations and outcomes between adults and elderly were still not well established.
Methods: We conducted a prospective study to evaluate the clinical manifestations of AMI at emergency department in Taiwan. Patients with unstable angina were excluded. The primary endpoint was all-cause mortality. The inpatient days, discharge activities, complications were collected for comparisons.                            
Results: Overall 210 consecutive cases with acute coronary syndrome were recruited in ER, 202 patients with AMI were enrolled for further analysis (66.3% STEMI and 33.7% NSTEMI). Among all AMI patients, 57 patients (28.2%) aged more than 65 years old. The overall inpatient days and total complications were not significantly different between adult and elderly patients. However, K-M survival analysis displayed that patients over the age of 75 years old was with poor event free survival rate of mortality (Log-rank test, P=0.03), especially for those patients with STEMI (Log-rank test, P=0.01). Cox regression exhibited that chest X-ray finding of cardiomegaly [adjusted hazard ratio (HR), 95% confidence interval (CI): 13.5, 1.27–144, P=0.03] and peak CK-MB levels (adjusted HR, 95% CI: 1.003, 1.001–1.004, P},
	issn = {2616-2717},	url = {https://ht.amegroups.com/article/view/5325}
}