TY - JOUR AU - Su, Po-Hua AU - Chen, Pang-Yen AU - Lee, Shih-Yi AU - How, Chorng-Kuang AU - Chien, Ding-Kuo AU - Chang, Wen-Han PY - 2019 TI - Comparison of clinical presentations and outcomes between adult and elderly acute myocardial infarction patients in emergency department JF - Health Technology; Vol 3 (September 2019): Health Technology Y2 - 2019 KW - N2 - Background: Acute myocardial infarction (AMI) is one of a leading cause of death. The clinical presentations and outcomes between adults and elderly were still not well established. Methods: We conducted a prospective study to evaluate the clinical manifestations of AMI at emergency department in Taiwan. Patients with unstable angina were excluded. The primary endpoint was all-cause mortality. The inpatient days, discharge activities, complications were collected for comparisons. Results: Overall 210 consecutive cases with acute coronary syndrome were recruited in ER, 202 patients with AMI were enrolled for further analysis (66.3% STEMI and 33.7% NSTEMI). Among all AMI patients, 57 patients (28.2%) aged more than 65 years old. The overall inpatient days and total complications were not significantly different between adult and elderly patients. However, K-M survival analysis displayed that patients over the age of 75 years old was with poor event free survival rate of mortality (Log-rank test, P=0.03), especially for those patients with STEMI (Log-rank test, P=0.01). Cox regression exhibited that chest X-ray finding of cardiomegaly [adjusted hazard ratio (HR), 95% confidence interval (CI): 13.5, 1.27–144, P=0.03] and peak CK-MB levels (adjusted HR, 95% CI: 1.003, 1.001–1.004, P Conclusions: The clinical presentations and outcomes may vary among adult AMI patients and older AMI patients. The chest X-ray finding of cardiomegaly and higher peak CK-MB levels may predict future mortality in AMI patients. The elderly patients over 75 years were with higher mortality after onset of AMI. UR - https://ht.amegroups.org/article/view/5325